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At 25 mg/kg/day, plasma AUC0-24 human resources levels in rats were 110 to 125 times above the degree exhibited in postmenopausal volunteers at the suggested dose.

Posted on February 22, 2007 by Admin

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It might be offered to ladies whose cancer did not react to first-choice medicines like tamoxifen.

Bisphosphonate treatment preserved bone quality in most individuals at threat of fracture.

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The terminal elimination half-life was 46.8 h, which resembled that observed in postmenopausal ladies treated with anastrozole for boob cancer cells.

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A typical carcinogenesis research in rats at dosages of 1.0 to 25 mg/kg/day(concerning 10 to 243 times the everyday max suggested human dose on a mg/m2 basis) provided by dental gavage for approximately 2 years disclosed a boost in the incidence of hepatocellular adenoma as well as carcinoma and uterine stromal polyps in females and also thyroid adenoma in males at the high dosage.

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Posted on February 22, 2007 by Admin

Filed under Uncategorized | Edit | 28 Comments